Every Celebrity Guest on Star-Studded Comedy Series, 'Only Murders in the Building'

Tony Award nominee Jesse Williams, who is best known for his role as Dr. Jackson Avery on Grey’s Anatomy, is set to join the cast of Only Murders in the Building for Season 3, Deadline confirms. He will play a documentarian with an interest in Mabel (Gomez).

British model and actress Cara Delevinge, who is famously known for her modeling career as well as roles in Paper Towns and Suicide Squad, frequently stars alongside Gomez in Only Murders in the Building. Initially a fan of Mabel's artwork, the two eventually form a romantic bond that still continues to unfold.

Appearing solely in Season 2, Rapaport plays a detective who investigates the murder. Rapaport began his career as an actor and comedian in the early 1990s and has since made over 100 appearances in film and television. His many film roles include True Romance (1993), Cop Land (1997), Big Fan (2009), and The Heat (2013).

Amy Schumer plays...Amy Schumer. Beginning her career as a stand-up comedian and then launching her own sketch show Inside Amy Schumer and now Hulu series Life of Beth, Schumer simply appears as herself, a comedian based in New York City.

Shirley Maclaine, who boasts numerous accolades over her seven-decade career, including six Academy Award nominations, enters the series in Season 2. Her credits are truly endless, notably including Around the World in 80 Days, The Children's Hour, and The Evening Star. Her appearance in the show marks Maclaine's return to television in over a decade.

Best known for her work on Saturday Night Live, Fey is an extremely impressive, successful writer and performer. She created the US sitcom 30 Rock, which ran for seven seasons in total, and also wrote film projects including Mean Girls (2004), Baby Mama (2008), Date Night (2010), Megamind (2010), Muppets Most Wanted (2014), Sisters (2015), Whiskey Tango Foxtrot (2016), Wine Country (2019), and Soul (2020). In Only Murders in the Building, Fey portrays Cindy Canning, the biggest name in true crime podcasts.

Da'Vine Joy Randolph portrays Detective Williams, a detective for the NYPD, who is repeatedly seen in scenes with the trio, warning them not to interfere with the investigation. Randolph has television credits on This Is Us and Empire as well as key roles in recent features such as Dolemite is My Name, The United States vs Billie Holiday, and The Lost City.

Jackie Hoffman, an actress, singer, and comedian known for her one-woman shows of Jewish-themed original songs and monologues, is also superbly funny in this series. She portrays Uma Heller, another resident in the apartment building, who suspects the trio (Gomez, Martin, and Short) to be responsible for the murder.

Gaining popularity from his role in the successful miniseries The People v OJ Simpson: American Crime Story, portraying the defense attorney, Nathan Lane stars as Teddy Dimas, a friend of Oliver's (Short) in Only Murders in the Building. 

Academy Award nominee and two-time Tony Award nominee Amy Ryan appears in both Season 1 and Season 2 of the series. Ryan, perhaps better known for working alongside Steve Carrell in The Office, is certainly not new to comedy. In the series' first season, she portrays Martin's love-interest-turned-suspect, which added plenty of suspense and comedy for viewers. 

Just as in real-life, Sting is a musician. He is known for being a member of the rock band The Police, releasing iconic songs including Let it Be, as well as having a successful solo career. This isn't Sting's first acting gig playing himself as he also starred in The Vicar of Dibley, Zoolander 2, and Ally McBeal. 

Winning the 2019 Tony Award for Best Featured Actress in a Musical for her performance in Oklahoma! is actress, author, and singer Ali Stroker. In Only Murders of the Building, Stroker plays Paulette, a proudly devoted fan of the trio's podcast.

Your favorite Glee character, Sue Sylvester, even makes her cameo in this series. Lynch appears as Charles’ (Martin) stunt double in matching shirts, suit jackets, and a pork pie hat. As an Emmy award-winning actress, she truly brings comedic gold in her own distinct ways to every series she stars in.  

Best known for her leading roles on Broadway, which include originating the role of Nina Rosario in the musical In the Heights as well as Elphaba in Wicked, Mandy Gonzalez plays Mabel's mother. Whilst Gonzalez was not cast as a major character, the relationship between her and Gomez is portrayed with bountiful meaning and concern, making their scenes extremely moving. 

Warning: spoilers ahead. In the Season 2 finale, Paul Rudd makes an appearance. Sadly, for Clueless fans, Rudd, who plays a Broadway actor, probably won't be around too long. Why? Well, he's the next season's murder victim. But unlike the previous seasons, he is actually not murdered in the building. But all bets are off because, with this hilarious cast, you just never know what's coming next.